Fundulopanchax kamdemi shares with all other Fundulopanchax species except those of the subgenus Paludopanchax 16 or more scales around the caudal peduncle versus 12 in Aphyosemion s.l. It is distinguished
from all Aphyosemion species and many Fundulopanchax except F. arnoldi, F. deltaensis, F. gularis, F. kribianus, F. ndianus, F. robertsoni, F. rubrolabialis, F. schwoiseri, F. sjoestedti, and F. walkeri by the high number of dorsal (15–18) and anal fin rays (16–19) (according to the descriptions and data in Huber 2000). It is distinguished from all Fundulopanchax species by its unique male coloration of a red longitudinal band on the middle of the sides versus no red band, with the exception of F. amieti, F. avichang, F. deltaensis and some individual specimens of F. ndianus, F. puerzli and F. spoorenbergi. It is distinguished from all Fundulopanchax species, except F. ndianus and some specimens of F. puerzli, by a red ventral band from the pelvic fins to the lower caudal fin base. F. kamdemi is distinguished from the latter species and most other Fundulopanchax
except F. spoorenbergi by the coloration of the unpaired fins as given below. Females can be distinguished from its congeners by the presence of an orange-red margin at the dorsal fin and a narrow red band at the base of the anal fin (Ref. 58752).